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Health and Fitness

Predictors and Therapies in Primary CNS Angiitis Outcomes

TOPLINE: Long-term outcomes in primary angiitis of the central nervous system (PACNS) were influenced by patient/disease factors; compared with no treatment, treatment with cyclophosphamide (alone or with steroids) was associated with a reduction in relapse rates. METHODOLOGY: This retrospective observational cohort study included 163 adults (median age, 48 years; 45% women) diagnosed with PACNS at …

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Glucose Monitoring Shows Dysglycaemia in Premature Infants

TOPLINE: In very low birth weight (VLBW) infants, continuous glucose monitoring (CGM) at 36 weeks of postmenstrual age (PMA) revealed subclinical dysglycaemia; male infants showed prolonged hyperglycaemia, and prior insulin therapy predicted extended hypoglycaemia. METHODOLOGY: Researchers evaluated the prevalence of dysglycaemia in VLBW infants at 36 weeks of PMA through CGM and investigated associated risk …

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Long-Acting Antibiotics Match Standard-of-Care Antibiotics

TOPLINE: In a large cohort, long-acting lipoglycopeptides (laLGPs) demonstrated comparable effectiveness to standard-of-care antibiotics for step-down treatment of serious Gram-positive bacterial infections in both individuals who used drugs and those who did not. METHODOLOGY: Standard antibiotic therapy for serious bacterial infections can be challenging due to stigma and logistical barriers associated with prolonged treatment. LaLGPs …

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Teens Oversleeping Post-Concussion May Have Worse Recovery

TOPLINE: Kids and teens sleeping longer, even as little as an hour more, during the first week after a concussion were more likely to have worse cognitive and somatic symptoms. Sleeping longer was also linked to persistent symptoms and slower recovery. METHODOLOGY: Researchers used data from a randomized clinical trial that took place across three …

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Decline of Nonrecommended HIV Care in Medicare

TOPLINE: Among Medicare beneficiaries with HIV, the proportion receiving at least one nonrecommended antiviral prescription decreased substantially from 5.1% in 2013 to 0.1% in 2021. METHODOLOGY: Clinical guidelines in 2017 recommended discontinuing older, more toxic antivirals in people with HIV. However, some people continue to take them due to several barriers to switching. This cross-sectional …

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The 6 Best Pre-Workouts for Men, According to Registered Dietitians

Best Overall Transparent Labs Bulk Based on our extensive testing, we found that Transparent Labs’ Bulk Pre-Workout has everything you need to increase your reps, energy, and focus during your workouts. Each serving contains 8 grams of citruline malate, an amino acid salt that enhances blood flow to your muscles while removing waste and increasing …

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