WASHINGTON — CMS officials responded to concerns from accountable care organization (ACO) leaders about growth, a substantial pending payment cut, and ideological opposition, speaking at the meeting of the National Association of ACOs (NAACOS) here last week. During a question-and-answer session with CMS Administrator Chiquita Brooks-LaSure, NAACOS CEO Clif Gaus, ScD, said the administration’s goal …
Tecovirimat (Tpoxx) was well tolerated among patients with monkeypox virus infection, though its efficacy in monkeypox is currently unclear, CDC researchers said. Among over 300 patients taking tecovirimat under the FDA-regulated Expanded Access Investigational New Drug (EA-IND) protocol, 6.9% were hospitalized after symptom onset, with a median duration of hospitalization of 4 days, reported Farrell …
Tecovirimat Safe in Monkeypox, but Efficacy Is Less Clear Read More »
Baseline amyloid levels predicted amyloid plaque response with donanemab, an investigational drug targeting N-terminal pyroglutamate beta-amyloid in early Alzheimer’s disease, a post hoc review of phase II TRAILBLAZER-ALZ data found. The rate of donanemab-induced amyloid reduction at 24 weeks was moderately correlated with the amount of baseline amyloid (r −0.54, P 0.001).p> Read More
PARIS — Treatment with a PD-L1 inhibitor held a survival advantage over single-agent chemotherapy for unfit non-small cell lung cancer (NSCLC) patients ineligible for platinum doublets, findings from the IPSOS trial showed. The randomized study met its primary endpoint, showing that atezolizumab (Tecentriq) significantly improved overall survival (OS) compared with physician’s choice of chemotherapy (HR …
Survival Bump in Unfit NSCLC With First-Line Immunotherapy Read More »
Now that bivalent Omicron BA.4/5 COVID boosters are becoming more widely available, MedPage Today asked about a dozen physicians if and when they’re planning to get the latest COVID shots. Many said they would take their boosters right away, but a few had other plans — including not taking a booster at all. Here are …
HBO’s House of the Dragon, based on Game of Thones author George R.R. Martin’s prequel Fire & Blood, follows the Targaryen royal family’s war of succession, with multiple princes and princesses vying for the Iron Throne. Much like Game of Thrones before it, House of Dragon features an ensemble cast, but Princess Rhaenyra Targaryen is …
Rhaenyra Could Be Pregnant in House of the Dragon Read More »
At least four years have passed since the death of Baelon Targaryen—the “Heir for a Day”—an event that opened the succession vacuum on House of the Dragon. The Queen, Alicent Hightower (Emily Carey), has since given birth to a son (the eldest son and first-in-line to the throne by gendered tradition) and now nurses another …
What Happened Last Night on House of the Dragon? Here’s Our Recap of Episode 4. Read More »
HBO’s Game of Thrones prequel House of the Dragon takes viewers back in time nearly 200 years to a period in history when House Targaryen ruled over the Seven Kingdoms, and has proceeded to tell the story of how the white-wigged family’s prosperous reign becomes endangered by an increasingly messy dispute over the line of …
Everything You Need to Know About House of the Dragon‘s Laenor Velaryon Read More »
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Image Group LA//Getty Images The next slate of Marvel Cinematic Universe projects was announced at the D23 expo this weekend, and among them is a different kind of team-up movie which will consist of several former villains and anti-heroes from previous stories. Sebastian Stan took to the stage to confirm that he will be reprising …
Sebastian Stan Just Introduced the Cast of Marvel’s Thunderbolts Movie Read More »