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Health and Fitness

Thyroid Storm Deaths Rose With Covid-19, Other Risk Factors

Orlando, Fla — A surge in mortality due to thyroid storm occurred in the US during 2020-2021, likely partially, but not entirely, due to the COVID-19 pandemic, a new analysis of people hospitalized with thyrotoxicosis in the National Inpatient Sample (NIS) between 2016 and 2021 showed. However, “the increased mortality observed was not solely attributable …

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Lymphoma: Dual-Targeting CAR T Shows Safety, Efficacy

TOPLINE: In a first in-human study, KITE-363, an anti-CD19/CD20 chimeric antigen receptor (CAR) T-cell therapy, showed high rates of response in patients with highly refractory large B-cell lymphoma (LBCL). The bicistronic, autologous CAR T-cell therapy, designed to prevent CD19 escape through the upfront targeting of CD19 and CD20, also showed an encouraging safety profile, with …

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Cardiac Risk Warning for Lamotrigine Challenged

Real-world data from two new studies showed no increased risk for cardiac issues in older adults with epilepsy taking the antiseizure medication (ASM) lamotrigine (Lamictal) vs levetiracetam. The findings add to growing evidence that may eventually lead the FDA to reconsider its current cardiac safety warning, researchers said. The FDA added the cardiac warning label …

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Daytime Sleepiness Tied to Risk for Early Death in Women

SEATTLE — Excessive daytime sleepiness (EDS) was associated with a significantly increased risk for all-cause mortality in women, results of a large observational study showed. After adjusting for health and demographic factors, women aged 50 and 65 years with high scores on the Epworth Sleepiness Scale (ESS) were 16% more likely to die from any …

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