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Health and Fitness

Nic von Rupp and Clément Roseyro’s Partnership Shows How Big Wave Surfing Is a Team Sport

THE SURFER IS typically depicted as a solitary figure. One person flowing with the force of nature, nothing but a board between them and the violence below the surface of the sea. This image is even starker in the world of big wave surfing, where athletes are dwarfed by massive walls of water as they …

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Danny Boyle Called Me From Church to Talk About 28 Years Later

The following story contains some spoilers for 28 Years Later. DANNY BOYLE IS Zoom calling me from church—and he’s excited about it. Mostly because this isn’t just any church, and he’s not there just for fun or spiritual clarity. This church is one of six that was designed by the famed English architect Nicholas Hawksmoor …

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Nic von Rupp and Clément Roseyro’s Partnership Shows How Big Wave Surfing Is a Team Sport

THE SURFER IS typically depicted as a solitary figure. One person flowing with the force of nature, nothing but a board between them and the violence below the surface of the sea. This image is even starker in the world of big wave surfing, where athletes are dwarfed by massive walls of water as they …

Nic von Rupp and Clément Roseyro’s Partnership Shows How Big Wave Surfing Is a Team Sport Read More »

Danny Boyle Called Me From Church to Talk About 28 Years Later

The following story contains some spoilers for 28 Years Later. DANNY BOYLE IS Zoom calling me from church—and he’s excited about it. Mostly because this isn’t just any church, and he’s not there just for fun or spiritual clarity. This church is one of six that was designed by the famed English architect Nicholas Hawksmoor …

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AI-Derived Risk Score May Improve Risk Stratification of Squamous Cell Carcinomas

An artificial intelligence (AI)-enabled prognostication system created through retrieval augmented generation (RAG) appears to offer significantly better predictive capability, particularly regarding poor outcomes, for cutaneous squamous cell carcinoma (cSCC) compared with the Brigham and Women’s Hospital (BWH) and American Joint Committee on Cancer Staging Manual, Eighth Edition (AJCC8) systems, according to a recently published study. …

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Guselkumab Clears Scalp Psoriasis Across Skin Tones

TOPLINE: In the VISIBLE trial, guselkumab led to significant and sustained improvements in scalp psoriasis severity and quality of life in patients with skin of color through 48 weeks. METHODOLOGY: Researchers evaluated outcomes in a cohort of patients in the phase 3b randomized VISIBLE trial, which included 102 adults with skin of color and scalp …

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Promising Weight-Loss Compound Targets Energy Expenditure

A new weight-loss compound targeting energy expenditure rather than appetite suppression showed early efficacy in a first-in-human study. The compound, SANA (MVD1; Eolo Pharma), activates creatine-dependent thermogenesis, a novel approach to obesity and metabolic disease compared to appetite suppression, explained Eolo Pharma CEO María Pía Garat. “To our knowledge, SANA is the only small molecule …

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Cardiovascular Risk Not Key in Presurgical Med Management

TOPLINE: The STOP-or-NOT study of patients undergoing major noncardiac surgery found no difference in the postoperative risk for death or major complications in those who continued or discontinued treatment with renin-angiotensin system inhibitors (RASi) prior to the procedure. A new post hoc analysis of the randomized controlled trial found stratification of preoperative cardiovascular risk does …

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Nerandomilast May Slow Down Progressive Pulmonary Fibrosis

TOPLINE: In a phase 3 study, nerandomilast administered at 18 mg or 9 mg twice daily slowed the progression of pulmonary fibrosis in adults with progressive pulmonary fibrosis. METHODOLOGY: In a previous study, nerandomilast, a preferential inhibitor of phosphodiesterase 4B, was found to slow the progression of idiopathic pulmonary fibrosis. The present phase 3, randomized …

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Gillette Fusion5 Razor Review: An Unbeatably Smooth Shave

MOST GROOMING PRODUCTS either solve present issues, like a moisturizer to hydrate dry skin, or prevent future ones, like sunscreen blocking sun damage. Razors, however, avoid creating new problems such as ingrown hairs, irritation, or cuts. It’s why Gillette Fusion5 remains the best razor for men, offering a smooth, close shave without any of the …

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