TNF Receptor 1 May Drive Pulmonary Arterial Hypertension Phenotype
New data reported in a presentation at the American College of Rheumatology (ACR) annual meeting showed that tumor necrosis factor (TNF) receptor 1 (TNFR1) rather than TNFR2 is responsible for TNF-mediated pulmonary endothelial and stromal pathology that causes pulmonary arterial hypertension (PAH), in a mouse model of connective tissue disease-associated PAH. In this exclusive MedPage …
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