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A promising drug delivery method could replace injections with pills

A promising drug delivery method could replace injections with pills

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Credit: CC0 Public Domain For chronic conditions such as rheumatoid arthritis, treatment often involves lifelong injections. Fear of needles, injection-associated infection and pain are responsible for patients skipping doses, which encourages the development of new delivery strategies that combine efficacy with limited side effects to treat patients adequately. Researchers at Baylor College of Medicine and …

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Protein Grb10 offers a potential new approach for treating obesity

Protein Grb10 offers a potential new approach for treating obesity

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Grb10 regulates leptin signaling by interaction with LepRb. Credit: Nature Metabolism (2023). DOI: 10.1038/s42255-022-00701-x For many people, keeping a healthy body weight can be a challenge. According to the Centers for Disease Control and Prevention, among adults 20 years old and over, the prevalence of obesity is 42% in the U.S. Obesity-related conditions, including heart …

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Study reveals huge extent of fungal disease in India

Study reveals huge extent of fungal disease in India

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A) Published reports of histoplasmosis by state of residence of patients. B) Published reports of histoplasmosis according the authors’ institution, by state. Credit: Open Forum Infectious Diseases (2022). DOI: 10.1093/ofid/ofac603 Researchers from India and Manchester have shown that over fifty million Indians are affected by serious fungal disease, 10% of which are from potentially dangerous …

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Study finds 3 percent of kids show increasing sensory issues in early childhood

Study finds 3 percent of kids show increasing sensory issues in early childhood

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Parallel-process trajectory classes of sensory features (5-class solution; full sample N=1,517) [estimated means with 95% confidence intervals]. †None of the parents had a college degree (or beyond). HYPER=sensory hyper-responsiveness; HYPO=sensory hypo-responsiveness; SIRS=sensory interests, repetitions and seeking behaviors. *p is less than .05; **p is less than .01; ***p is less than .001 (odds ratio tests). …

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