Ken Jennings bravely embarrassed himself on TV, and it had to do with an old debt due to James Holzhauer. The duo were recently on Jeopardy! Masters, where Ken was host and James was a contestant. As fans may remember, back in 2020, the trivia wizards competed on Jeopardy! The Greatest of All Time (GOAT), …
CHICAGO — In a pair of mid-stage trials, newer targeted therapies demonstrated meaningful levels of activity against HER2-positive biliary tract cancers in pretreated patients with advanced disease. Cohort 1 of the global HERIZON-BTC-01 study, which included 80 treatment-refractory patients, showed that 41.3% (95% CI 30.4-52.8) responded to zanidatamab, an investigational bispecific monoclonal antibody that targets …
Novel Anti-HER2 Drugs ‘Impressive’ in Advanced Biliary Cancer Read More »
Quizzes > Weekly News Quiz — You passed medical training, now see if you can pass our weekly quiz by MedPage Today Staff June 3, 2023 The 24-hour news cycle is just as important to medicine as it is to politics, finance, or sports. At MedPage Today, new information is posted daily, but keeping up …
CHICAGO — An “adaptive response” treatment strategy identified a subset of patients with HER2-positive early breast cancer who benefited from a chemotherapy-free treatment plan, according to the phase II PHERGain trial. The strategy is based on evaluating an early response to a dual HER2 blockade with trastuzumab (Herceptin) and pertuzumab (Perjeta) with 18F-FDG PET imaging …
Chemo-Free Approach Works in Subset of Patients With HER2+ Early Breast Cancer Read More »
MILAN — About half of patients receiving infusions of a novel uricase analog, along with a proprietary rapamycin formulation, in two similarly designed phase III studies got their serum urate under control, after multiple other medications had failed to do so, a researcher said here. Dubbed SEL-212, the treatment combines a pegylated form of uricase …
MILAN — An investigational protein drug called dazodalibep with broad-spectrum activity against autoimmune pathways reduced symptoms of Sjögren’s syndrome in a two-stage, phase II randomized trial with a unique design. Called ALISS, the placebo-controlled trial targeted two different populations, each reported in separate presentations at the European Alliance of Associations for Rheumatology (EULAR) annual meeting. …
First-in-Class Sjogren’s Drug Passes Mid-Stage Test Read More »
When the first season of Manifest began airing on NBC in 2018, it seemed at first to be yet another successor to LOST: an ensemble drama revolving around a missing flight and cryptic, supernatural occurrences. But the drama series soon found its audience, thanks to some propulsive, increasingly wacky plotting, and it ran for three …
Immediately after getting off a long-haul flight, Chris Hemsworth does exactly one thing: he hits the gym to fight his way through jet lag. The actor just shared a look at his latest workout on Instagram after arriving in Los Angeles and making his way directly to celebrity trainer Grant Roberts’ gym, where he announced …
Watch Chris Hemsworth Try to Beat Jet Lag With an Intense Workout Read More »
Chad Michael Murray is looking even fitter in his early forties than he was during his peak heartthrob years. The actor, who rose to fame playing Lucas Scott in the teen drama One Tree Hill, just shared a glimpse of his lean, defined physique in a shirtless video over on his wife Sarah Roemer’s Instagram …
Chad Michael Murray Looks Shredded in a New Shirtless Instagram Video Read More »
When Spider-Man: Into the Spider-Verse came out in 2018, it felt like a reinvention of the superhero story. Stunning animation, strong voice acting, and a stellar storyline made the movie one of the biggest Marvel releases outside of the main MCU franchise. In November 2018, it was no surprise when Variety announced the film would …
Everything We Know About the Across the Spider-Verse Sequel, Beyond the Spider-Verse Read More »