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Health and Fitness

REI Patagonia Sale November 2024: Take up to 50% off Editor-Loved Outdoor Gear

WE’RE DEEP INTO FALL, which means it’s time to pull out those cold weather garments. It’s also a perfect time to freshen up that wardrobe — especially when retailers like REI are dropping prices on editor-favorite brands like Patagonia. The outdoor clothing brand behind some of our favorite pieces is currently up to 50 percent …

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Sexplain It: Perimenopause Has Killed My Wife’s Libido. I’m Now a Horny Mess.

I’m Zachary Zane, a sex columnist and author of Boyslut: A Memoir and Manifesto. Over the years, I’ve had my fair share of sexual experiences, dating and sleeping with hundreds of people of all genders and orientations. In doing so, I’ve learned a thing or two about navigating issues in the bedroom (and many other …

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Brews, Bubbles, & Booze: Stroke Risk and Favorite Drinks

A growing body of research explores the link between stroke risk and regular consumption of coffee, tea, soda, and alcohol. This research roundup reviews the latest findings, highlighting both promising insights and remaining uncertainties to help guide discussions with your patients. Coffee and Tea: Good or Bad?  In the INTERSTROKE study, high coffee consumption (> …

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PFAS May Affect Kidneys via Gut Microbes, Blood Metabolites

TOPLINE: Greater exposure to per- and polyfluoroalkyl substances (PFAS) is linked to reduced kidney function in young adults, mediated by changes in the gut microbiome and metabolites, including reduced anti-inflammatory bacteria and metabolites. METHODOLOGY: Exposure to PFAS is associated with an increased risk for chronic kidney disease, yet studies examining the mechanisms linking PFAS to …

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Leukemia Drug Shows Promise in Lewy Body Dementia

Nilotinib, a drug approved by the US Food and Drug Administration (FDA) to treat chronic myeloid leukemia, improved biomarkers and cognitive outcomes in patients with dementia with Lewy bodies (DLB) in a phase 2 randomized, double-blind, placebo-controlled trial.  The findings align with an earlier study that showed possible disease-modifying effects of nilotinib in patients with …

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Tirzepatide Slashes Progression From Prediabetes to T2D

SAN ANTONIO – Once-weekly tirzepatide (Zepbound) reduced the risk for progression from prediabetes to type 2 diabetes (T2D) by more than 90% at 3 years and continued to maintain dramatic levels of weight loss achieved earlier, but these benefits began reversing when the drug was stopped.  The findings, from the subset of 1032 individuals with …

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Louis Cancelmi Fits Perfectly Into The Penguin as Rex Calabrese

The following story contains spoilers for The Penguin episode 7, “Top Hat.” IF THERE’S ONE thing we know about the Matt Reeves universe of The Batman, it’s that everything we’re seeing exists with purpose.The Batman gave us an epic glimpse into Gotham City in the early days of Bruce Wayne’s run as Batman, and now …

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November Brooks Running Shoe Sale: Save up to 40% on Editor-Tested Sneakers

BLACK FRIDAY DEALS are still a couple of weeks away, but the sales are already coming in hot. Among said steals: Brooks, which has a bunch of serious steals on some of our favorite running shoe models across Amazon and Zappos. Our team sifted through their clearance sections to find the remaining markdowns on Brooks …

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