Health and Fitness

A study presented at the San Antonio Breast Cancer Symposium examined whether tumor mutational burden (TMB) was associated with outcomes in hormone receptor-positive, HER2-negative metastatic breast cancer patients treated with either pembrolizumab (Keytruda) or chemotherapy. Findings showed that patients with high TMB had numerically more favorable survival when treated with the immune checkpoint inhibitor. In …

Can Tumor Mutational Burden Guide Treatment in Metastatic Breast Cancer? Read More »

Best Overall Winter Running Shoe Hoka Clifton 9 GTX Cons Can be prone to slippage on slick surfaces Hoka’s Clifton 9 is one of the brand’s most popular shoes, and for good reason—it’s our favorite shoe for daily training. It’s uppers are comfortable and fit most foot shapes, the midsole provides plenty of squish for …

The Best Winter Running Shoes for 2025, Tested by Editors and Marathoners Read More »

Best Treadmill Overall NordicTrack Commercial 1750 Treadmill Now 13% OffCredit: Courtesy of Retailer Cons 10-year frame warranty is subpar The NordicTrack 1750 has been a long-standing favorite among MH fitness editors and hardcore indoor runners for years, and with good reason: It’s an all-around winner. The 16-inch touchscreen is responsive and compatible with iFIT programming, …

The Best Treadmills to Buy in 2025, Tested by Experts and Runners Read More »

HE’S SIX FOOT four, with an oval contoured face, deep-hued eyes, and looks that could kill—and frequently do. He’s 2024’s sexiest man alive. No, not inveterate goof John Krasinski, who won People‘s title this year, but the shambling, towering, blood-sucking villain in Robert Eggers’ Nosferatu, Count Orlok. (Although whether or not “alive” applies here may …

Count Orlok Is 2024’s Sexiest Man Read More »

I’m Zachary Zane, a sex columnist and author of Boyslut: A Memoir and Manifesto. Over the years, I’ve had my fair share of sexual experiences, dating and sleeping with hundreds of people of all genders and orientations. In doing so, I’ve learned a thing or two about navigating issues in the bedroom (and many other …

Sexplain It: I’m Worried My GF Will Leave Me for Someone With a Bigger Dick Read More »

Best Massage Gun Therabody Theragun Pro Now 20% OffCredit: Amazon Work out your tired muscles with the fifth generation Theragun Pro. This massager boasts a 300-minute battery life and five percussion settings to target your pain points. The handheld device’s unique triangular design offers multiple ways to grip it, as well as four different arm …

9 FSA/HSA Eligible Fitness Items, Recommended by Our Editors Read More »

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