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Health and Fitness

How Aaron Taylor-Johnson Became a Master Archer (and a Flawed Dad) for 28 Years Later

IF THERE’S ONE thing Aaron Taylor-Johnson has made clear on screen through the years, it’s that he’s a born survivor. That’s never been more evident than in Danny Boyle’s new horror-thriller 28 Years Later, though the complex and flawed characters he’s played have often struggled to adapt to the difficult circumstances they’ve been dealt in …

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Stem Cell-Derived Islets Still Producing Insulin at 1 Year

CHICAGO — Ten people with type 1 diabetes, who had recurrent severe hypoglycemia and hypoglycemic unawareness, have remained insulin-independent for over a year following allogeneic stem cell-derived islet-cell therapy with immunosuppression, according to new phase 1/2 data from the multicenter FORWARD study sponsored by Vertex Pharmaceuticals. The insulin-producing therapy VX-880, now named zimislecel, is delivered …

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Population-Level Weight Loss Seen With Primary Care Protocol

CHICAGO — Encouraging patients to talk with their primary care physicians about weight management led to increased visits for obesity, population-wide weight loss, and increased revenue, researchers at the University of Colorado Anschutz School of Medicine (CU Anschutz) reported here at the American Diabetes Association (ADA) 85th Scientific Sessions. The researchers presented data from a …

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Novel GLP-1 Agonist Promotes Safe and Effective Weight Loss

Ecnoglutide, a novel glucagon-like peptide-1 (GLP-1) receptor agonist, was significantly more effective than placebo for inducing weight loss in adults with overweight or obesity, based on data from more than 600 individuals, results of the SLIMMER trial showed.  In addition, ecnoglutide significantly improved other key cardiometabolic risk factors including waist circumference, blood pressure, lipid profile, …

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Orforglipron Lowers A1c, Weight in Early Type 2 Diabetes

CHICAGO — The investigational non-peptide small-molecule oral GLP-1 agonist orforglipron significantly reduced A1c over 40 weeks in adults with early type 2 diabetes, according to the results of ACHIEVE-1 sponsored by Eli Lilly.  In the trial, orforglipron reduced A1c to the 6.5% range and produced clinically meaningful weight loss with a safety profile similar to …

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28 Years Later‘s Ending Introduces Jack O’Connell’s Jimmy—and Starts a Whole New Story

The following story contains spoilers for 28 Years Later. AFTER MORE THAN two decades, director Danny Boyle and writer Alex Garland have finally returned to the scene of 2001’s horror/thriller 28 Days Later—and it’s proven to be worth the wait and then some (28 Weeks Later, released in 2007, is not terrible, but it didn’t …

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